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Agarwal, R.
- Clinical Profile, Pattern of Disease, Duration of Stay and Outcome of Patients Admitted in RICU at Tertiary Care Centre of Rohilkhand Region Bareilly
Authors
1 Department of Pulmonary (Chest) Medicine, Rohikhand Medical College & Hospital, Bareilly, IN
Source
The Indian Practitioner, Vol 69, No 7 (2016), Pagination: 23-27Abstract
Introduction: Respiratory intensive care unit(RICU) is an area within hospital which is well equipped and under control of specialised team of doctors, nurses and paramedical staff for providing all possible health facilities to the patient. It is also a specialised place for the monitoring and treatment of patients with acute respiratory failure due to primary respiratory cause and of patient with acute or chronic respiratory failure.
Aim: The aim of this study was to determine the clinical profile, pattern of disease, duration of stay and outcome of patients admitted in RICU at tertiary care centre of Rohilkhand Medical College and Hospital (RMCH), Bareilly.
Methodology: For the practical approach the study was conducted on 144 patients of the RICU. The analysis included patients who were hospitalised in the RICU of Deptt. of Pulmonary Medicine, Rohilkhand Medical College and Hospital, Bareilly from May 2014 until May 2015. Results: There were 144 admission during the study period. 102 were male and 42 were female. 46% were referred from the Emergency department (ED) and 40% of patients came from other ICU and hospitals. The most common complaints of patients was breathlessness in 86.1% and cough 68.02%. Most patients had admission in the ICU because of Respiratory Disorders and were ≥ 50 yrs. Average ICU stay was 4.5 days. About 48% of patients showed response to Oxygen inhalational therapy, but 23% patients were put on mechanical ventilator. > 60% patients were discharged from RICU, 16% died and 15% patient discharged and referred to higher centres.
Conclusion: Respiratory problems are the major reason for an RICU admission. Most common indication for admission was Type II respiratory failure and most common cause was acute exacerbation (AE) of COPD. > 70% of patients were improved and discharged.
Keywords
Intensive Care Unit, Respiratory Failure, Acute Exacerbation, Emergency Department, Outcome.References
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- Forest Cover Monitoring and Prediction in A Lesser Himalayan Elephant Landscape
Authors
1 Indian Institute of Remote Sensing, Indian Space Research Organisation, Dehradun - 248 001, IN
Source
Current Science, Vol 115, No 3 (2018), Pagination: 510-516Abstract
We have monitored the forest cover depletion in parts of Assam and Arunachal Pradesh over an area of 42,375 km2 in an elephant landscape falling in the Lesser Himalaya, North East India and report the results here. The US Army topographic maps (1924) and multi-date satellite images (1975, 1990, 2000 and 2009) were visually interpreted on-screen for post-classification comparison and forest cover change detection. The exercise showed continuous high loss of forest cover during the study period. A land area having 17,846.27 km2 forest in 1924 was depleted to 12,514.56 km2 by 1975, 11,861.75 km2 by 1990, 10,808.92 km2 by 2000 and 10,256.58 km2 by 2009, thereby indicating a constant decrease in forest cover by 12.59%, 1.54%, 2.48% and 1.31% respectively. The total loss in forest cover was estimated to be about 7590 km2 from 1924 to 2009. The Cellular Automata Markov Model has predicted a further likely decrease of 9007.14 km2 by 2028. In general, more districts of Assam than Arunachal Pradesh and more plains than hills faced deforestation. We have identified increasing human population and subsequent demand on the land for cultivation as major reasons for forest cover depletion.Keywords
Change Detection, Deforestation, Elephant Landscape, North East India, Satellite Images.References
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- Aldrin Induce Acute Toxicity at Enzymatic and m-RNA Expression Levels in Zebrafish
Authors
1 Laboratory of Analytical and Molecular Toxicology (Forensic Chemistry and Toxicology Laboratory), Institute of Forensic Science, Gujarat Forensic Sciences University, Sector 09, Gandhinagar – 382007, Gujarat, IN
Source
Toxicology International (Formerly Indian Journal of Toxicology), Vol 25, No 1 (2018), Pagination: 48-58Abstract
Aldrin is a systematic toxicant, belongs to cyclodiene class of organochlorine pesticide and banned due to its toxic, bioaccumalative and persistent nature but still detected from environmental components. Present study includes the assessment of aldrin toxicity at two sublethal concentrations in zebrafish. A total 81 zebrafish were divided into three groups viz. group 1: Control, group 2 and 3: Exposed groups which were given 3 mg/mL and 6 mg/mL of aldrin, respectively for 24 hours. The markers of oxidative stress viz. antioxidant enzymes (superoxide dismutase, catalase and glutathione peroxidase) were examined in terms of biochemical activities and gene expression. Acute exposure of aldrin (both concentrations) caused significant alteration in antioxidant enzymes activities and gene expression in liver, kidney and brain tissues, which were more prominent in brain in concentration dependent manner. Study provides a baseline data to understand alterations in enzymatic activity and expression leading to toxic manifestation of aldrin in aquatic animals.Keywords
Aldrin, Gene Expression, Organochlorine, Oxidative Stress, Zebrafish.References
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